Brunswick Laboratories Improves Productivity with the Centrifan PE

"Now with the revolutionary new Centrifan PE, we can remove solvents much faster and safer."

Dr. Jianxin Chen, Brunswick Laboratories

About: Brunswick Laboratories is a Massachusetts-based independent contract laboratory and research organization providing analytical and R & D services to the nutraceutical, pharmaceutical, food and cosmetic industries.

Problem: Brunswick Laboratories utilizes the Yamazen Automated Flash Chromatography System (AI-580) with Luknova and Agela normal phase / reverse phase columns (C18 and HILIC) in their chemistry Lab. Multiple fractions are typically collected after the Flash LC run and solvents must be removed from the fraction collection tubes prior to advancing the sample to the next analytical step. They used a conventional rotary evaporator to accomplish the solvent removal task. The process was slow as the rotorvap could only process one fraction at a time and the instrument cumbersome for the task at hand as it required coolant and a vacuum connection. They were also concerned with bumping and splashing that sometimes occurred during the rotorvap process that could destroy valuable samples.

Solution: Brunswick Laboratories turned to the Centrifan PE Personal Evaporator as a fast, safe way to remove solvents from multiple fraction collection tubes simultaneously. The Centrifan PE employs a novel, recirculating evaporation technique that operates without vacuum and eliminates the potential for cross contamination and sample loss caused by solvent bumping or splashing. As a result, Brunswick Laboratory has improved lab productivity by substituting the rotorvap with the Centrifan PE. They are able to dry more samples in less time and no longer risk losing valuable samples caused by vacuum-based evaporation techniques.

"This unique instrument works very well. It is smooth and quick, no bumping or splashing, and can evaporate multiple fraction tubes simultaneously instead of drying the tubes one at a time on a rotorvap," said Dr. Jianxin Chen, R & D Director, Brunswick Laboratories.